Our Story, Est. 1995

Why does high-end skincare brands cost so much?

"Well, it doesn't have to be. We set out to develop advanced dermatologically approved products with long-term in mind. A sustainable affordable premium products at affordable SA prices "


Value for money!

Suitable for all skin types including sensitive, dry to oily and fair to dark skin tone.

What makes DERMASURE & ZONE Skincare so different?

In a world with so much information and choice, Dermasure and Zone Skincare was developed to help with effective affordable skincare, to the essentials that naturally nourish and nurture the skin. 

Our products ethos kindness to the earth, and kind to your skin. Formulated by leading Dermatologists, with a commitment to natural, simple living.

Each component is gentle on the skin and to avoid skin irritation. Every ingredient is selected for its unique healing qualities and ability to easily penetrate the skin.

Our vision is to instil a daily ritual of effective affordable self-care, which translates into a loving appreciation for who you are, just as you are.

Our ethos is being mindful to your daily skincare routine. It's an act of selfcare. It's a simple and sustainable ritual.

Your beauty is natural. It's non-toxic for you and the environment. It's an authentic and relaxed attitude toward beauty.

Ageing is graceful and honours the stage of your life your are in. Your skin care routine supports skin health and repair. Alongside lifestyle and nutrition. 

Words from Smiley van Zyl (Founder), and his passion to make a difference in people's daily lives. 


"We created an effective skincare range with the help of leading experts in the field of skin care. To bring a product to market that not only makes a significant difference but with affordability as a key component, so that both women and men can maintain their skin care over the long-term." 


From pure passion to reality, the DERMASURE Pharmaceutical range was born, a South African company established in 1995. The ZONE Anti-Wrinkle range was established 9 years later in 2004 after overwhelming requests from our loyal customers.

We thank you (our client) daily for making all of this possible. Much appreciated!

Both ranges were developed by a large panel of leading Dermatologists and select Skin Therapists and used in a continuous advisory capacity for the actual formulations and continuous trails to find the optimal formula for each product.   

"Our CORE FOCUS is to develop unique dermatologically approved products, surrounded by leading Dermatologists and select Skin Therapists to help manufacture in SA, developed for South African conditions, at affordable South African prices."  


A complete skincare range that will make a significant difference, rather than following cosmetic trends.

It's suitable for all skin types including sensitive, dry to oily and fair to dark skin tone and helps repair visible signs of ageing and reduces wrinkles (face, frown & eye lines, upper lip, neck, chest & hands) leaving your skin revitalized.

For both women and men.

From Anti-Wrinkle facial cream to Acne Treatment to Eczema Relief to Problem Scalp or wanting a Daily Skincare Pack to Sun Protection Pack, we have you covered

"We plan to extend the ZONE range in the coming months after careful consideration from your feedback. Watch the space with our new product launch mid-2021!"  


We would also like to assure you that all the DERMASURE and ZONE packaging materials that you come into contact with are hygienically sealed and pre-sanitized.

All our products are hypo-allergenic, paraben-free, non-greasy, non-comedogenic are not tested on animals.

We offer medical-grade skin care products that are specially formulated according to pharmaceutical standards of purity, potency, and stability.

All active ingredients, and the concentrations and dosing protocols in which they are used, are supported by data published in the peer-reviewed medical literature.

As pharmaceutical and compounding experts, we formulate with high percentages of proven actives in ideal pH levels. Active ingredients are selected based on proven efficacy, safety and biocompatibility in peer reviewed medical trials.

We incorporate pharmaceutical grade ingredients with advanced delivery technologies to ensure all ingredients reach the target receptor sites within the dermal layers.

Because formulations are science-based and contain medicinal percentages of actives, the products are significantly different than other products on the market, which often include only trace amounts of these expensive active ingredients.

Manufacturing Laboratory:

All the products are formulated and manufactured in a facility regulated by the South African Pharmacy Council (SAPC), the regulator established in terms of the Pharmacy Act, 1974 (Act 53 of 1974). We are committed to the highest, medical-grade formulation standards, and uses only pharmaceutical-grade ingredients. Products are produced in small batches to ensure optimal potency and safety. The most rigorous pharmaceutical manufacturing standards are followed to ensure safe and effective formulations.

We stock at Dermatologists, GP's, Leading Skin Clinics, Pharmacies, Takealot and Dischem.

We have various packs available: Acne Treatment Pack, Eczema Relief Pack, Daily Skincare Pack, Sun Protection Pack & Anti-Wrinkles Range. 

Contact Details:

Any questions?

Chat to Smiley: WhatsApp Me (click) 

Smiley's Mobile: +27 82 412 7955 (Founder) 
Alternative Mobile: +27 60 646 9608 
Email: dermasure@wol.co.za

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